Organic Chemistry & Interfaces (_COrInt_) team Abstract Lichens biosynthesize a wide variety of secondary metabolites, which are often specific. Among these metabolites, xanthones are a family of molecules comprising nearly 120 compounds in lichens, divided into four main structural groups. 1,350 species of lichens containing xanthones have been recorded, the majority of which are crustose lichens that produce chlorinated lichexanthones. These lichen-specific xanthones possess a 1,3,6-trihydroxy
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